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Nano-ecol

Sanimed International and National Institute of Research – Materials Physics formed a partnership with our mission to achieve a prototype electrostatic plants, able to overcome impediments generation nanofibers.

S.C. Sanimed International Impex S.R.L.

Membrii echipei Poziția ocupată Gradul științific
Maier Stelian Sergiu Director de proiect CS II
Angheloiu Marin Cercetător CS III
Crețoiu Dragoș Cercetător CS I
Kamerzan Crina Cercetător CS III
Serdaru Maria Cercetător CS II
Balaș Cristina Cercetător CS III
Ardelean Florin Bogdan Cercetător Asistent de cercetare
Irimia Laurențiu Cercetător Inginer dezvoltare tehnologică I
Hideg Mircea Cercetător Inginer dezvoltare tehnologică I
Mihai Adina Cercetător Inginer dezvoltare tehnologică I
Gheorghe Cristofor Lucian Cercetător Tehnician I Studii superioare
Ciobanu Cristina Cercetător Tehnician

Institutul Național de Cercetare – Dezvoltare pentru Fizica Materialelor

Membrii echipei Poziția ocupată Gradul științific
Matei Elena Responsabil de proiect CS II
Diculescu Victor Constantin Cercetător CS III
Beregoi Mihaela Cercetător Asistent de cercetare
Evanghelidis Alexandru Cercetător Asistent de cercetare
Cioca Eugen Mihai Inginer Inginer dezvoltare tehnologică I
Dobrescu Gabriel Inginer Inginer dezvoltare tehnologică I
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Nano-ecol

nano-ECol – Technology transfer project

Technology and equipment for producing collagen-based nanofibrillary structures for resorbable wound dressings

As a result of project completion, the company’s research infrastructure in the field of collagen, collagen forms, and collagen-based products will be enriched with a novel demonstrative prototype meeting the imposed requirements for the shift to the TRL5 level. Based on the results of the technical and economical analyses performd on the prototype operated at micro-pilot level, the S.C. Sanimed International Impex S.R.L. company will consider the scaling-up feasibility and opportunity, i.e. self-producing / purchasing an industrial electrospinning system, intended for the manufacture of micro- / nano-filamentay and bioresorbable dressings, starting from specifically formulated atelocollagen-based mixtures.
During the project activities concerning the prototype building and framework technology elaboration, the project partners will jointly conceive the corresponding technical documentation and some scientific works on the electrospinning subject.

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Nano-ecol

nano-ECol – Technology transfer project

Technology and equipment for producing collagen-based nanofibrillary structures for resorbable wound dressings

The goal of the nano-Ecol project is to implement the electrospinning technology for S.C. Sanimed International Impex S.R.L., aiming at obtaining electrospun protein-based nanofibers. The main objectives to this goal are: (1) to design and build the prototype of an electrospinning system, able to overcome the difficulties commonly related to the obtaining of nanofibers starting from highly hydrophilic and easily degradable polymeric compounds, such as scleroproteins (namely, atelocollagen); (2) to develop a framework technology for the manufacture of protein-based nanostructured substrates and a particular technology/process applicable to the atelocollagen solutions produced by S.C. Sanimed International Impex S.R.L.; (c) to scale up the technology at pre-industrial level.
The implementation of this project will produce the leap from TRL4 to TRL5 on the technology maturity scale for the atelocollagen electrospinning technology, i.e. moving from a technology validated in lab, to a technology validated in relevant environment.

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Nano-ecol

nano-ECol – Technology transfer project

Technology and equipment for producing collagen-based nanofibrillary structures for resorbable wound dressings

The nano-ECol project proposal aims to develop an innovative technology and to implement a demonstrative prototype at the Technology Readiness Level TRL5, for the production of micro- and nano-fibrillar substrata usable as absorbable dressings for wounds and burns. The micro- and nano-fibers will be obtained by electrospinning, starting from colloidal solutions of atelocollagen currently manufactured at S.C. Sanimed International Impex S.R.L. In this respect, the project aims at shifting/promoting the INFIM SPIN 1.0 prototype, developed through a previous project by the National Institute of Materials Physics (INCDFM), and preliminary tested for its atelocollagen electrospinning capacity, from the TRL4 to the TRL5.
The main technological challenges faced by the nano-Ecol project are: (i) preserving atelocollagen macromolecule in a quasi-native state, (ii) providing the products reproducibility, (iii) producing substrates with an area of tens of square dm and thickness of 3 … 12 mm, (iv) providing a prototype able to work at micropilot scale, with at demand-formulated electrospun compositions, (v) providing rapid structural and dimensional prototyping, (vi) scaling-up the prototype and related technology to industrial level.
The project will benefit from the facilities and logistics of five research centers, of which two belong to Sanimed, and three to INCDFM. Services and facilities provided by all mentioned centers are detailed on the ERRIS platform.
The Sanimed co-funding represents 67.63% of the sum allocated to the company from the public budget, i.e. 25.27% of total buget, and 39.04% of the total payroll.
The expected outcomes of the project meet the Sanimed interest in expanding the range of products and addressability, by manufacturing resorbable dressings with tailored shape, structure and density, obtained from compositions formulated at physician’s request, in order to satisfy specific pacient needs.